4,4-DMAR

What is 4,4-DMAR?

4,4-DMAR is a synthetic stimulant drug that belongs to the phenethylamine and amphetamine classes. It is also known by its chemical name 4,4’-dimethylaminorex. The drug is a potent and long-acting stimulant that has gained notoriety due to its high potential for abuse and addiction.

History of 4,4-DMAR

4,4-DMAR was first synthesized in the 1960s by a team of chemists led by Dr. George Revell at the University of California, San Francisco. The drug was developed as a potential appetite suppressant and was investigated for its potential as a treatment for obesity.

In the 1980s, 4,4-DMAR was briefly marketed as a recreational drug under the street name “Serotoni”. However, its use as a recreational drug was short-lived due to the severe adverse effects associated with its use.

Chemical properties of 4,4-DMAR

The chemical structure of 4,4-DMAR consists of a phenethylamine core with a dimethylamino group and a methylene bridge connecting the two rings. It has a molecular formula of C11H16N2 and a molar mass of 176.26 g/mol.

4,4-DMAR is a white crystalline powder that is soluble in water and organic solvents such as ethanol and acetone. It is usually administered orally or intranasally.

Pharmacology of 4,4-DMAR

4,4-DMAR works by increasing the levels of the neurotransmitters dopamine, norepinephrine, and serotonin in the brain. It achieves this by inhibiting the reuptake of these neurotransmitters, thereby increasing their concentration in the synaptic cleft.

The increased levels of these neurotransmitters lead to the stimulant effects of 4,4-DMAR, such as increased energy, alertness, and euphoria. However, the drug also has significant side effects, such as anxiety, paranoia, and cardiovascular problems.

Effects of 4,4-DMAR

The effects of 4,4-DMAR are similar to other stimulants, such as amphetamines and cocaine. Users of the drug report increased energy, alertness, and euphoria. However, the drug also has significant side effects, such as anxiety, paranoia, and cardiovascular problems.

4,4-DMAR is a potent and long-acting drug, and its effects can last for up to 24 hours. The drug is highly addictive, and chronic use can lead to tolerance, dependence, and addiction.

Legality of 4,4-DMAR

4,4-DMAR is classified as a Schedule I drug under the United States Controlled Substances Act. It is also banned in several other countries, including the United Kingdom, Germany, and Sweden.

Conclusion

4,4-DMAR is a synthetic stimulant drug that has gained notoriety due to its high potential for abuse and addiction. The drug is a potent and long-acting stimulant that has effects similar to other stimulants, such as amphetamines and cocaine. However, the drug also has significant side effects, such as anxiety, paranoia, and cardiovascular problems. The drug is highly addictive, and chronic use can lead to tolerance, dependence, and addiction.