Introduction
Md-php, also known as Methylenedioxy Pyrovalerone, is a synthetic stimulant drug belonging to the cathinone class. It is a new psychoactive substance that has gained popularity among recreational drug users and has been sold online as a designer drug. Md-php is chemically similar to other cathinone drugs, such as α-PVP and MDPV. The drug is typically sold in the form of a fine powder or crystals and is consumed via oral, nasal, or intravenous administration. Due to its stimulant properties, Md-php is often used for its euphoric effects and to increase energy and concentration levels.
History
History
Md-php was first synthesized in the 1960s as a part of research into the stimulant drug pyrovalerone. The drug was later rediscovered in the early 2010s by clandestine laboratories and marketed as a designer drug. Since then, it has gained popularity among recreational drug users and has been subject to legal control in some countries.
Chemical Properties
Chemical Properties
Md-php has a chemical formula of C17H23NO3 and a molecular weight of 289.4 g/mol. The drug is a white to light yellow crystalline powder with a melting point of 170-175 °C. It is soluble in water, ethanol, and methanol, and has a pKa value of 8.44 at 25 °C.
Mechanism of Action
Mechanism of Action
Md-php is a potent stimulant that acts on the central nervous system by increasing the levels of dopamine, norepinephrine, and serotonin in the brain. The drug achieves this by blocking the reuptake of these neurotransmitters, leading to their accumulation in the synaptic cleft. The increased levels of dopamine and norepinephrine result in increased energy, alertness, and concentration, while the increased serotonin levels contribute to the drug’s euphoric effects. Md-php has been shown to have a higher affinity for the dopamine transporter than other cathinones, such as MDPV and α-PVP, which may contribute to its increased potency.
Effects and Risks
Effects and Risks
The effects of Md-php can be similar to other stimulant drugs, such as cocaine and amphetamines. These effects include euphoria, increased energy and focus, and reduced appetite. However, the drug also has some potential risks and side effects. These can include:
- Increased heart rate and blood pressure
- Anxiety and agitation
- Insomnia and sleep disturbances
- Psychotic symptoms, such as paranoia and hallucinations
- Increased risk of seizures and cardiovascular events
- Addiction and dependence
Legal Status
Legal Status
The legal status of Md-php varies by country. In some countries, such as the United States, the drug is classified as a Schedule I controlled substance, meaning that it is illegal to possess, distribute, or manufacture. In other countries, such as Germany and the United Kingdom, the drug is subject to legal control and is classified as a psychoactive substance.
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