5C-AKB48

What is 5C-AKB48?

5C-AKB48 is a synthetic cannabinoid that has been used as a recreational drug. It is a potent agonist of the CB1 and CB2 receptors, which are the primary targets of delta-9-tetrahydrocannabinol (THC), the active component of cannabis. AKB48 is also known as N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide.

Chemical Properties

5C-AKB4 has the chemical formula C23H30N2O with a molecular weight of 358.51 g/mol. It has a melting point of 98-99 °C and a boiling point of 569.8 °C at 760 mmHg. AKB48 is a white powder that is insoluble in water, but soluble in organic solvents such as ethanol and DMSO.

Pharmacology

5C-AKB48 acts as a potent agonist of the CB1 and CB2 receptors, which are the primary targets of delta-9-tetrahydrocannabinol (THC), the active component of cannabis. It is believed to produce its effects by binding to the CB1 receptor in the brain, which leads to the release of dopamine and other neurotransmitters. This results in a feeling of euphoria and relaxation.

Mechanism of Action

5C-AKB48 acts by binding to the CB1 and CB2 receptors in the brain and other parts of the body. It has a high affinity for the CB1 receptor, which is primarily found in the brain, and a lower affinity for the CB2 receptor, which is mainly found in the immune system. Binding to the CB1 receptor leads to the activation of downstream signaling pathways, which ultimately leads to the release of neurotransmitters such as dopamine, serotonin, and norepinephrine.

Effects

The effects of 5C-AKB48 are similar to those of cannabis but more potent. Users report feeling relaxed, euphoric, and sometimes even hallucinations. The effects can last for several hours and can be unpredictable. Other effects may include increased heart rate, dry mouth, red eyes, and increased appetite. Long-term use of 5C-AKB48 can lead to addiction, tolerance, and withdrawal symptoms.

Legal Status

5C-AKB48 is a controlled substance in several countries, including Sweden, where it is classified as a “narcotic substance” under the Narcotic Drugs Punishments Act. It is also banned in many other countries, including the United States, the United Kingdom, and Canada.

Conclusion

5C-AKB48 is a synthetic cannabinoid that acts as a potent agonist of the CB1 and CB2 receptors. It produces effects similar to those of cannabis but more potent. The use of 5C-AKB48 can lead to addiction, tolerance, and withdrawal symptoms. It is a controlled substance in several countries, including Sweden, and is banned in many other countries. It is important to use caution when using 5C-AKB48 and to be aware of its potential risks and legal status.