5C-APB

What is 5C-APB?

5C-APB is a synthetic empathogen and entactogen that belongs to the phenethylamine and amphetamine classes. It is also known as 1-(benzofuran-5-yl)-N-methylpropan-2-amine or 5-(2-amino-propyl)benzofuran. 5C-APB is closely related to the popular drug MDA, and is sometimes referred to as “MDA’s little cousin.”

History and Development

5C-APB was first synthesized in 1993 by David E. Nichols and his team at Purdue University. The compound was initially developed as a potential antidepressant but was never marketed for this use. Instead, 5C-APB became popular as a recreational drug in the early 2010s.

Chemical Properties

5C APB is a crystalline powder that is typically white or off-white. It has a molecular weight of 219.3 g/mol and a molecular formula of C13H17NO. 5C APB is soluble in water, ethanol, and dimethyl sulfoxide (DMSO), but is insoluble in hexane.

Pharmacology

5C-APB is a potent serotonin and norepinephrine-releasing agent, with additional activity as a mild dopamine-releasing agent. It is thought to exert its effects primarily through the release of serotonin and norepinephrine, leading to feelings of euphoria, empathy, and increased sociability. The drug has a duration of action of 6-8 hours and is typically taken orally in doses ranging from 100-200 mg. Canabis

Effects

The effects of 5C-APB are similar to those of other empathogens and entactogens, such as MDMA and MDA. Users typically report feelings of euphoria, empathy, and increased sociability, as well as heightened sensory perception and a feeling of being “in the moment.” Some users also report mild psychedelic effects, such as visual distortions and altered perceptions of time.

Side Effects

Like other drugs in the amphetamine and phenethylamine classes, 5C-APB can cause a range of side effects. These may include increased heart rate, elevated blood pressure, insomnia, loss of appetite, and dry mouth. The drug may also cause headaches, dizziness, and nausea in some users. Prolonged or heavy use of 5C APB may also lead to more serious side effects, such as serotonin syndrome and cognitive impairment.

Legal Status

The legal status of 5C-APB varies depending on the country and jurisdiction. In some countries, such as the United Kingdom, the drug is a controlled substance and is illegal to possess, distribute, or manufacture. In other countries, such as the United States, 5C APB is not currently a controlled substance under federal law but may be subject to regulation under state or local laws.

Conclusion

5C-APB is a potent empathogen and entactogen that is closely related to the popular drug MDA. It is known for its ability to induce feelings of euphoria, empathy, and increased sociability, and is typically taken orally in doses ranging from 100-200 mg.