Introduction
5cl-ADB-A is a synthetic cannabinoid that was first identified in synthetic cannabis products in Japan in 2018. It is a highly potent agonist of the CB1 receptor, which is the primary target of THC, the main psychoactive component of cannabis.
Chemical Properties
5cl-ADB-A is a derivative of a series of compounds called indazole-3-carboxamides, which are structurally similar to other synthetic cannabinoids like JWH-018 and AM-2201. It has a molecular formula of C20H27N3O2Cl and a molecular weight of 377.91 g/mol.
Synonyms
5cl-ADB-A is also known by other names, including 5-CL-ADB-A, 5-chloro-ADB-A, and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-chloropentyl)-1H-indazole-3-carboxamide.
Appearance
5cl-ADB-A typically appears as a white or off-white powder, and may also be sold in the form of tablets, capsules, or e-liquid for use in vaporizers.
Effects
Like other synthetic cannabinoids, 5cl-ADB-A can produce a range of psychoactive effects, including euphoria, relaxation, and altered perception of time and space. However, it is important to note that synthetic cannabinoids are not the same as natural cannabis, and their effects can be unpredictable and potentially dangerous.
Pharmacology
5cl-ADB-A binds to the CB1 receptor with high affinity, which is what produces its psychoactive effects. However, it is also known to have a relatively high affinity for the CB2 receptor, which is primarily expressed in immune cells and may play a role in inflammation and pain.
Health Risks
The use of synthetic cannabinoids like 5cl-ADB-A can pose significant health risks, including the potential for overdose and addiction. Synthetic cannabinoids have also been associated with a range of negative side effects, including nausea, vomiting, anxiety, and seizures.
Legality
The legal status of 5cl-ADB-A varies by country and jurisdiction. In many places, it is illegal to sell or possess synthetic cannabinoids, and they may be classified as controlled substances.
Sweden
In Sweden, 5cl-ADB-A is classified as a “health hazard” and is illegal to sell, possess, or use.
United States
In the United States, 5cl-ADB-A is classified as a Schedule I controlled substance, which means that it is illegal to manufacture, distribute, or possess without a DEA license.
European Union
In the European Union, 5cl-ADB-A is not currently listed as a controlled substance under the United Nations Single Convention on Narcotic Drugs, but individual member states may have their own laws and regulations regarding its sale and use.
Conclusion
5cl-ADB-A is a potent synthetic cannabinoid that can produce a range of psychoactive effects, but its use can also pose significant health risks. It is important to exercise caution when using any psychoactive substance, and to be aware of the legal status of such substances in your jurisdiction.
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