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5-PPDI, or 5-phenyl-1H-pyrrolo[2,3-b]pyridine-3,4-dione, is a psychoactive substance that belongs to the pyrrolopyridine class. This chemical compound is known to have potent stimulant effects and has been found to be closely related to other stimulant compounds such as MDPV and α-PVP.

Chemical Properties

5-PPDI is a white or off-white crystalline powder that is soluble in organic solvents such as methanol, ethanol, and acetone. The chemical formula of 5-PPDI is C16H10N2O2, and its molar mass is 262.3 g/mol.


Like other stimulant compounds, 5-PPDI works by increasing the levels of dopamine and norepinephrine in the brain. These neurotransmitters are responsible for regulating mood, reward, and motivation, which is why stimulants can produce feelings of euphoria, increased energy, and heightened alertness.

Studies on the pharmacology of 5-PPDI are limited, but it is believed that the compound acts as a potent reuptake inhibitor of dopamine and norepinephrine. This means that it blocks the reuptake of these neurotransmitters, causing them to accumulate in the brain and produce its stimulating effects.

Side Effects

As with other stimulant compounds, 5-PPDI can produce a range of side effects, some of which can be severe. The most common side effects of 5-PPDI include increased heart rate, elevated blood pressure, and vasoconstriction. Users may also experience feelings of anxiety, paranoia, and agitation, as well as insomnia, loss of appetite, and sweating.

Long-term use of 5-PPDI can also lead to more serious health problems, including cardiovascular and neurological damage. Chronic use of stimulants can also lead to addiction, and withdrawal from these substances can cause depression, fatigue, and cravings.

Legal Status

In most countries, including the United States and Sweden, 5-PPDI is a controlled substance and is illegal to manufacture, distribute, or possess. The possession and distribution of 5-PPDI can result in criminal charges, fines, and imprisonment.


In summary, 5-PPDI is a potent stimulant compound that works by increasing the levels of dopamine and norepinephrine in the brain. While it can produce feelings of euphoria and increased energy, it can also produce a range of negative side effects and can be highly addictive. Due to its potential for harm, 5-PPDI is illegal in most countries and should be avoided. If you or someone you know is struggling with addiction, seek professional help immediately.


100g, 200g, 300g, 500g


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